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A multi-agency report links a decline in antimicrobial consumption (AMC) in Europe from 2014 to 2021 with a decline in overall antimicrobial resistance (AMR) in humans and livestock.
The fourth joint report on integrated analysis of AMC was published yesterday. EFSA Journal by the European Center for Disease Prevention and Control (ECDC), the European Food Safety Authority (EFSA) and the European Medicines Agency (EMA). For the first time, this report focuses on AMC and AMR. Escherichia coli Bacteria.
Use in livestock decreased by 44%
From 2014 to 2021, AMC decreased by 44% in food-producing animals, but remained relatively stable in humans. Escherichia coli Antibiotic resistance is declining in both animals and humans, and the study authors suggest this is a sign that alarming trends in AMR can be reversed with the right actions and policies.
EFSA Executive Director Bernhard Ullu, DVM, said reducing the use of antibiotics in livestock would help. “Most countries that have reduced antibiotic use have observed a corresponding decline in resistance levels,” he told EFSA. press release. “This means national efforts are working. It also underlines the EU’s commitment to a One Health approach that protects both animals and global public health.”
The authors also found that antibiotics such as carbapenems, third- and fourth-generation cephalosporins, and quinolones are associated with resistance to these antibiotics. Escherichia coli From people. Similarly, the use of quinolones, polymyxins, aminopenicillins, and tetracyclines in livestock is associated with resistance to these antibiotics. Escherichia coli Among those animals. The relative strength of associations varied markedly by antimicrobial class, microorganism, and sector.
Bacterial resistance in humans may be linked to bacterial resistance in food-producing animals, the researchers said. for example, Campylobacter jejuni and Campylobacter coliviruses that can be found in food-producing animals can be spread to people through food.
Tackling the AMR public health threat
ECDC Director Andrea Ammons, MD, MPH, said further efforts to reduce unnecessary AMC are needed to address the AMR public health threat. “In Additionally, it is essential to strengthen immunization programs and strengthen infection prevention and control practices in communities and health care settings to reduce the need for antibiotics,” she said in the release. Ta.
AMR kills more than 35,000 people in the European Union and European Economic Area and generates 11.7 billion euros ($12.7 billion) in health costs each year, the report said.
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